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|В ||Modality (device)В ||ParameterВ ||AdvantagesВ ||DisadvantagesВ |
|Regional stiffnessВ ||DopplerВ ||cfPWVaВ |
Can assess other cardiac and arterial features, e.g. LV hypertrophy, strain
Does not require a specific device
Faster than applanation tonometry
Identification of anatomical landmarks aids repeatability of measurement position
Can detect occlusive/atherosclerotic lesions that may affect PWV
In addition: В
Sites of measurement limited by acoustic window
Lacks versatility for anatomical variations
Method of distance measurement overestimates distance
Calculation of cfPWV includes iliac and femoral arteries and excludes ascending aorta
|Mechano- transducer (Complior)В ||cfPWVВ ||In addition: В ||In addition: |
Variations in transit time algorithms used
Underestimates PWV compared with applanation tonometry
Cannot provide local wall assessment, where aortic condition may vary
|Applanation tonometry (SpyghmoCor)В ||cfPWVВ ||В ||In addition: |
Two consecutive recordings needed, heart rate variability may cause confounding
Local wall assessment not possible
|Local stiffnessВ ||CMRВ ||aPWV and ADВ |
Local and regional assessment of aorta possible
Relatively operator independent
Full visualization of the entire vessel
Imaging planes can be precisely placed with good repeatability
Greater spatial and temporal resolution (especially 3Tesla CMR) to study the temporal shift over smaller distances
Measurement not affected by anatomical variations, peripheral vascular disease or problems with using probes to detect waveforms
Other aspects of cardiac and arterial function can be assessed, e.g. strain and deformation
Focal measurement may be prone to sampling error
Image analysis can be time-consuming and user dependent
Longer examination time than other methods
Not possible with patients with metal implants, or with claustrophobia
PP is usually determined non-invasively and peripherally as it is more feasible than invasive measurement
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